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Image Search Results
Journal: British Journal of Cancer
Article Title: Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells
doi: 10.1038/sj.bjc.6602663
Figure Lengend Snippet: Effect of NRP-1 overexpression on the antiapoptotic protein, MCL-1. Analysis of apoptosis-related gene expression by gene microarray revealed a three-fold increase in gene expression of the antiapoptotic Bcl-2 homologue, MCL-1 . In order to confirm upregulation of the MCL-1 protein, Western blot analysis of the FG mock transfectants and NRP-1 transfectants was performed. A nearly two-fold increase in MCL-1 protein expression was observed in the NRP-1-overexpressing cells. Actin levels are shown as a loading control.
Article Snippet: Biotin-labelled cDNA probes were prepared using the AmpoLabeling-LPR Kit (SuperArray, Frederick, MD, USA) and hybridised to the
Techniques: Over Expression, Expressing, Microarray, Western Blot